MmuPV1 and HPV E6 Elevate Nuclear Accumulation of IKK? to Impair NF-κB Signaling to Promote Persistent Infection
Preston T Shepherd, Kayla R Duxbury, Zachary Morris, James C Romero-Masters
This study shows MmuPV1 and HPV16 E6 oncoproteins disrupt NF-κB signaling by increasing nuclear IKKα localization, suggesting a shared mechanism in papillomavirus persistence.
bioRxiv · Nov 9, 2026 · PreprintMicrobiology