TIR immune signaling is blocked by phosphorylation to maintain plant growth
Jun Li, Sisi Chen, Bo Yu, Qingzhong Li, Ruijia Liu, Zaiqing Wang, Li Wan, Yang Zhao
This study identifies phosphorylation of a conserved serine residue in TIR domains as a mechanism to block NADase activity and repress immune signaling, balancing growth and defense in plants and animals.
bioRxiv · Apr 9, 2025 · PreprintPlant Biology