Linezolid Acts as a Selective Inhibitor of the JAK2V617F Mutation
Anisa Azatovna Gumerova, Christoph Schaniel, Zixing Huang, Althea Agdamag, Shuhui Liu, Alessandro Principi, Jacob S. Kazmi, Francisco Fueyo‐González, Cui J, Georgii Pevnev, C Yang, Zehra Berna Tumoglu, Xin Gao, Tony Yuen, Yelena Z. Ginzburg, , H C Li
This paper shows linezolid selectively inhibits JAK2V617F mutant cells in PV models, reducing disease burden without affecting wild-type cells.
bioRxiv · Jun 3, 2026 · PreprintCancer Biology