Christoph Schaniel

This paper shows linezolid selectively inhibits JAK2V617F mutant cells in PV models, reducing disease burden without affecting wild-type cells.

This study investigates how stem cell transplantation (SCT) restores immune function in refractory Crohn's disease by analyzing immune cell remodeling and HSC heterogeneity using single-cell RNA sequencing and functional assays.

The paper identifies cardiotoxic drug signatures using bulk transcriptomics and integrates them with genomic and single-cell data to predict toxicity mechanisms.

The paper identifies KLF16 as an inhibitory regulator of osteogenic differentiation through transcriptomic analysis of human iPSC-derived cells and in vivo validation.

This study identifies and characterizes hPSC-derived FOXA2+ progenitor cells with enhanced ventricular cardiomyocyte differentiation potential.