Author

Zelun Li

Victor Chang Cardiac Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:diffusion model· 1

Frequent Co-Authors

Emily S. W. WongiD· 2 shared Paola Cornejo‐Páramo· 2 shared Aaron WenteleriD· 1 shared Aniketh Janardhan ReddyiD· 1 shared Cameron Smith· 1 shared Cesar Miguel Valdez CordovaiD· 1 shared David T. HumphreysiD· 1 shared Lithin Karmel Louis· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersSynthetic Biology

Emily S. W. WongORCID

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2 papers

Recent·Most cited

DNA-Diffusion: Leveraging Generative Models for Controlling Chromatin Accessibility and Gene Expression via Synthetic Regulatory Elements

Lucas F. daSilva, Simon Senan, Zain Munir Patel, Aniketh Janardhan Reddy, Sameer Gabbita, Zach Nussbaum, Cesar Miguel Valdez Cordova, Aaron Wenteler, Noah Weber, Tin M. Tunjic, Talha Ahmad Khan, Zelun Li, Cameron Smith, Matei Bejan, Lithin Karmel Louis, , Luca Pinello

DNA-Diffusion uses diffusion models to generate cell type-specific regulatory DNA sequences that modulate chromatin accessibility and gene expression.

bioRxiv · Feb 1, 2024 · PreprintSynthetic Biology

A Bag-Of-Motif Model Captures Cell States at Distal Regulatory Sequences

Paola Cornejo‐Páramo, Xuan Zhang, Lithin Louis, Yihua Yang, Zelun Li, David T. Humphreys, Emily S. W. Wong

The paper introduces BOM, a computational model that captures cell-type-specific regulatory information in distal sequences by analyzing TF binding motifs, showing it outperforms deep learning models with fewer parameters.

bioRxiv · Jan 3, 2024 · PreprintBioinformatics