Author

Simon Senan

Broad InstituteORCID 0009-0003-7501-2102Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 1 Approach:deep learning· 1 Approach:diffusion model· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:software / tool· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Aaron WenteleriD· 1 shared Aniketh Janardhan ReddyiD· 1 shared Cameron Smith· 1 shared Cesar Miguel Valdez CordovaiD· 1 shared Emily S. W. WongiD· 1 shared Lithin Karmel Louis· 1 shared Luca PinelloiD· 1 shared Lucas F. daSilvaiD· 1 shared

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2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperSynthetic Biology

Aaron WentelerORCID

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1 paper

Recent·Most cited

Synthetic BiologybioRxivPreprintFeb 1, 2024

DNA-Diffusion: Leveraging Generative Models for Controlling Chromatin Accessibility and Gene Expression via Synthetic Regulatory Elements

Lucas F. daSilva, Simon Senan, Zain Munir Patel…·Luca Pinello

DNA-Diffusion uses diffusion models to generate cell type-specific regulatory DNA sequences that modulate chromatin accessibility and gene expression.

32 citations

humanDNA methylation

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