Aaron Wenteler

Varformer prioritizes drug targets and variants by integrating variant and gene features using a transformer model, achieving high precision across diverse benchmarks.

SHOT-CCR improves classification of genetic perturbations in Cell Painting datasets by reducing batch effects through biologically guided adversarial training.

This study benchmarks zero-shot single-cell foundation model embeddings for perturbation effect prediction and finds they do not consistently improve over baseline models under distribution shift.

DNA-Diffusion uses diffusion models to generate cell type-specific regulatory DNA sequences that modulate chromatin accessibility and gene expression.