Single-cell spatial transcriptomics of inherited retinal degeneration reveals broad and focal organization of disease responses
Aya A. Abu-Alfa, Ryan Passino, Zhangyong Wei, Sumasri Kotha, Arjun Raj, Katherine E. Uyhazi
The paper uses single-cell spatial transcriptomics to map transcriptional responses to inherited retinal degeneration across the retinal axis, revealing both broad and focal spatial organization of disease-related gene expression.
bioRxiv · Oct 7, 2026 · PreprintNeuroscience