Zhenhua Li

DECIPHER integrates disentangled representation learning and prototype-based cell-type deconvolution across molecular modalities

DECIPHER improves cell-type deconvolution across molecular modalities by combining disentangled representation learning with prototype-based methods, showing robust performance in simulated and real datasets.

Discovery of a taxusin-mediated route to baccatin III enables its complete biosynthesis in engineered microbes

The paper identifies a novel biosynthetic pathway for baccatin III production using engineered microbes, achieving its complete de novo synthesis through enzymatic validation and pathway engineering.