Zhenhua Li

This paper develops an EV-based platform for efficient circRNA delivery, enabling sustained protein expression and therapeutic applications in dendritic cell targeting and myocardial fibrosis.

This study develops a liquid-liquid phase-separated hydrogel to deliver mitochondria for treating myocardial ischemia-reperfusion injury, showing improved mitochondrial function and cardiac recovery.

This paper introduces a strategy called TopCare to reduce doxorubicin-induced cardiotoxicity by temporarily increasing P-gp expression in cardiomyocytes, showing improved survival and cardiac function in mice and pigs.