Liriodendrin Targets PFKFB3 to Suppress Inflammatory Phenotypic Transition and Vascular Remodeling in Pulmonary Hypertension
Qingye Zeng, Zhenzhen Duan, Qian Liu, Lei Yang, Sha Zhao, Yicheng Lv, Xiaoxun Huang, Jincheng Zhang, Jingyang Su, Zhiqian Lu, Shaowen Liu, Deping Kong
This study identifies liriodendrin as a compound that targets PFKFB3 to reduce inflammation and vascular remodeling in pulmonary hypertension.
bioRxiv · Aug 5, 2026 · PreprintPhysiology