Qian Liu

Redox oscillation frequency reshapes antibiotic resistance-gene expression through metabolic and ecological selection in a freshwater community

The paper shows that redox oscillation frequency increases antibiotic resistance gene expression in a freshwater microbial community through metabolic and ecological selection, without altering resistance gene sequences.

Liriodendrin Targets PFKFB3 to Suppress Inflammatory Phenotypic Transition and Vascular Remodeling in Pulmonary Hypertension

This study identifies liriodendrin as a compound that targets PFKFB3 to reduce inflammation and vascular remodeling in pulmonary hypertension.

Artificial Intelligence of Things-Enhanced Automated Surveillance System for Global Antimicrobial Resistance in Food Supply Chain

This paper develops an AIoT-integrated system for automated AMR surveillance in food supply chains, achieving high accuracy and cost reduction.

The small MAF transcription factor MAFG co-opts MITF to promote melanoma progression

This study identifies MAFG as a driver of melanoma progression by interacting with MITF to alter gene expression and promote a dedifferentiated melanoma phenotype.

IFITM1 inhibits Henipavirus membrane fusion by trapping ephrinB2 receptors in fusion-unfavorable membrane nanodomains.

This paper shows IFITM1 inhibits henipavirus entry by sequestering ephrinB2 in membrane domains that hinder virus-cell fusion.

AM-DMF-SCP-pro: An Ultrafast and Streamlined Nanolitre-Scale Lab-on-a-Chip Platform for Single-Cell Proteomics and Tumor Microenvironment Profiling

AM-DMF-SCP-pro enables rapid, low-background single-cell proteome profiling in complex samples by streamlining sample preparation and reducing background interference.

Single-cell transcriptomic atlas of mouse oocyte development from growth to ovulation

This study creates a single-cell transcriptomic atlas of mouse oocyte development from growth to ovulation using a new platform and integrates transcriptomic and morphological data to identify temporal shifts in gene expression.

Phytic Acid (InsP6) Activates HDAC3 Epigenetic Axis to Maintain Intestinal Barrier Function

The paper shows that phytic acid activates the HDAC3 epigenetic axis to maintain intestinal barrier function, with therapeutic potential in inflammatory bowel disease.

Riemann-GNN: Causal Reasoning on Hyperbolic Riemannian Manifolds for Interpretable Drug-Disease Prediction

Riemann-GNN uses hyperbolic geometry and causal inference to predict drug-disease associations with high accuracy and interpretability.

Integrated data models on Receptor-Like Kinases for novel domain discovery and functional inference in the plant kingdom

The paper develops an integrated RLK data model across 528 plant genomes, identifies 524,948 RLK members, discovers two novel families, and provides tools for functional inference and ecological adaptation analysis.