Author

Zhigang Ji

Baylor College of Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Assay:electronic health records· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alfred L. GeorgeiD· 2 shared Carlos G. VanoyeiD· 2 shared Edward C. CooperiD· 2 shared Aamir R. ZuberiiD· 1 shared Amanda S. LindyiD· 1 shared Ana G. Chavez· 1 shared Anastasios V. TzingounisiD· 1 shared Anuraag Madabushi· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersNeuroscience

Alfred L. GeorgeORCID

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2 papers

Recent·Most cited

Plural molecular and cellular mechanisms of pore domain KCNQ2 encephalopathy

Timothy J Abreo, Emma C. Thompson, Anuraag Madabushi, Heun Soh, Nissi Varghese, Carlos G. Vanoye, Kristen Springer, Kristen Springer, Jim Johnson, Scotty Sims, Zhigang Ji, Ana G. Chavez, Miranda J. Jankovic, Bereket Habte, Aamir R. Zuberi, , Edward C. Cooper

The paper investigates the molecular and cellular mechanisms of KCNQ2 encephalopathy through structural analysis, functional assays, and an animal model, revealing multiple pathogenic effects of the G256W variant.

eLife · Jan 6, 2025Peer-reviewedNeuroscience

High-throughput Evaluation of Epilepsy-associated KCNQ2 Variants Reveals Functional and Pharmacological Heterogeneity

Carlos G. Vanoye, Reshma R. Desai, Zhigang Ji, Sneha Adusumilli, Nirvani P. Jairam, Nora F. Ghabra, Nishtha Joshi, Eryn Fitch, Katherine L. Helbig, Dianalee McKnight, Amanda S. Lindy, Fanggeng Zou, Ingo Helbig, Edward C. Cooper, Alfred L. George

This study evaluates 79 KCNQ2 variants using automated patch clamp recording, revealing functional and pharmacological heterogeneity and genotype-dependent retigabine responses.

JCI Insight · Feb 1, 2022Peer-reviewedNeuroscience