GNG2-MRAS interaction regulates SHOC2-dependent RAF activation and MAPK signaling
Govinda R. Navale, Bamidele Towolawi, Colin Christoff, Sravani Malasani, Zhiwei Liu, Zhihong Wang
This study identifies GNG2 as an inhibitor of the SMP complex by binding MRAS, disrupting its assembly and inhibiting MAPK signaling.
bioRxiv · Nov 3, 2026 · PreprintBiochemistry