Cross-kingdom miRNA delivery by Panax notoginseng-derived EVs restores neuronal function after ischemic injury
Yuanyuan Yu, Na Tan, Zhifeng Xu, Zhijian Tan, Tao Wang, Huimin Liu, Le Xu, Dan Lu, Yamei Tang, Hongcheng Mai
This study shows that Panax notoginseng-derived extracellular vesicles deliver miRNAs to neurons, reducing ischemic injury by modulating stress responses and mitochondrial function.
bioRxiv · Aug 8, 2025 · PreprintPharmacology & Toxicology