Distinct mechanisms of neutralization by antibodies targeting a conserved pneumovirus F epitope
Sebastian Ols, Rodrigo Arcoverde Cerveira, Andrew J. Borst, Erick Bermúdez-Méndez, Florian A. Gegenfurtner, Elise Eray, Connor Weidle, Marcos C. Miranda, Zhitong Peng, Kenneth D. Carr, Rebecca Skotheim, Jana Kochmann, Natalie Brunette, Klara Lenart, Leo Hanke, , Karin Loré
This study identifies two antibody classes that neutralize pneumovirus by targeting a conserved epitope, revealing distinct mechanisms of action through structural and functional analyses.
bioRxiv · Sep 24, 2026 · PreprintImmunology