Re-evaluating the role of nucleosomal bivalency in early development
Rohan N. Shah, Adrian T. Grzybowski, Jimmy Elias, Zhonglei Chen, Takamitsu Hattori, Carolin C. Lechner, Peter W. Lewis, Shohei Koide, Beat Fierz, Alexander J. Ruthenburg
This study re-evaluates the bivalency model using a new ChIP method, finding widespread bivalency that does not resolve with differentiation and is not specific for poised developmental genes.
bioRxiv · Sep 9, 2021 · PreprintMolecular Biology