Author

Zhongming Liang

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Approach:large language model· 1 Organism:mouse· 1

Frequent Co-Authors

Guihai FengiD· 2 shared Guole LiuiD· 2 shared Hongmei WangiD· 2 shared Jiahao ZhangiD· 2 shared Jingxi DongiD· 2 shared Xin LiiD· 2 shared Yana LiuiD· 2 shared Yuanchun ZhouiD· 2 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Guihai FengORCID

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2 papers

Recent·Most cited

GeneCompass: Deciphering Universal Gene Regulatory Mechanisms with Knowledge-Informed Cross-Species Foundation Model

Xiaodong Yang, Guole Liu, Guihai Feng, Dechao Bu, Pengfei Wang, Jie Jiang, Shubai Chen, Qinmeng Yang, Hefan Miao, Yiyang Zhang, Zhenpeng Man, Zhongming Liang, Zichen Wang, Yaning Li, Zheng Li, , Zeyuan Zhang

GeneCompass is a cross-species foundation model pre-trained on single-cell transcriptomes from human and mouse, integrating biological knowledge to improve gene regulatory mechanism understanding and downstream tasks.

Cell Research · Oct 7, 2024Peer-reviewedBioinformatics

CellPolaris: Decoding Cell Fate through Generalization Transfer Learning of Gene Regulatory Networks

Guihai Feng, Xin Qin, Jiahao Zhang, Wuliang Huang, Yiyang Zhang, Wentao Cui, Shirui Li, Chen Yao, Wenhao Liu, Yao Tian, Yana Liu, Jingxi Dong, Ping Xu, Zhenpeng Man, Guole Liu, , Xin Li

CellPolaris uses transfer learning to generate cell-type-specific gene regulatory networks from transcriptomic data, achieving state-of-the-art results in predicting regulatory factors and simulating cell fate transitions.

bioRxiv · Sep 25, 2023 · PreprintBioinformatics