Gut Commensal Bacteria-Derived Methionine is Required for Host Reproduction by Modulating RNA m6A Methylation of the Insulin Receptor
Qiuyuan Zhang, ZhuRong Deng, Xiaoxue Li, Jiao Qiao, Ziniu Li, Peipei Liu, Alfred M. Handler, Bruno Lemaître, Weiwei Zheng, Hongyu Zhang
This study shows that gut bacteria provide methionine, which modulates RNA m6A methylation of the insulin receptor, thereby promoting host reproduction in Bactrocera dorsalis.
Cell Reports · Jun 24, 2025Peer-reviewedMicrobiology