Proteomic Profiling Reveals Age-Related Changes in Transporter Proteins in the Human Blood-Brain Barrier
Xujia Zhou, Mina Azimi, Niklas Handin, Andrew M. Riselli, Bianca Vora, Eden Chun, Zilong Dang, Eric Jinsheng Huang, Sook Wah Yee, Per Artursson, Kathleen M. Giacomini
This study uses proteomic profiling to identify age-related changes in transporter proteins in human brain microvessels, revealing alterations in BBB permeability and drug disposition.
Scientific Reports · Dec 26, 2025Peer-reviewedDevelopmental Biology