Author

Niklas Handin

Novavax (Sweden)ORCID 0000-0003-1838-0681Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew M. RiselliiD· 1 shared Anna-Karin E. PalmiD· 1 shared Behdad Zarnegar· 1 shared Berit CarowiD· 1 shared Bianca VoraiD· 1 shared Carolina Lunderius-Andersson· 1 shared Eden ChuniD· 1 shared Emelie Bringeland· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperDevelopmental Biology

Andrew M. RiselliORCID

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2 papers

Recent·Most cited

Developmental BiologyScientific ReportsPeer-reviewedDec 26, 2025

Proteomic Profiling Reveals Age-Related Changes in Transporter Proteins in the Human Blood-Brain Barrier

Xujia Zhou, Mina Azimi, Niklas Handin…·Kathleen M. Giacomini

This study uses proteomic profiling to identify age-related changes in transporter proteins in human brain microvessels, revealing alterations in BBB permeability and drug disposition.

12 citations

humanproteomics

𝕏 PostBluesky

Immunologynpj VaccinesPeer-reviewedAug 5, 2025

Matrix-M(R) adjuvant triggers inflammasome activation and enables antigen cross-presentation through induction of lysosomal membrane permeabilization

Behdad Zarnegar, Berit Carow, Jens Eriksson…·Carolina Lunderius-Andersson

This study shows Matrix-M adjuvant induces lysosomal membrane permeabilization, enabling antigen cross-presentation and IL-1β/IL-18 secretion, which contributes to its adjuvant effect.

11 citationstop 5%

mouseproteomics

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