ProteomeGenerator: A framework for comprehensive proteomics based on de novo transcriptome assembly and high-accuracy peptide mass spectral matching
Paolo Cifani, Avantika Dhabaria, Zining Chen, Akihide Yoshimi, Emily A. Kawaler, Omar Ibrahim Abdel-Wahab, John Thomas Poirier, Alex Kentsis
ProteomeGenerator enables sample-specific proteome discovery by integrating transcriptome sequencing and high-accuracy mass spectrometry, identifying non-canonical protein isoforms and improving proteogenomic analysis.
Journal of Proteome Research · Oct 8, 2018Peer-reviewedBioinformatics