Pressure-induced membrane tension mechanically opens the germinant receptor GerA ion channel to trigger bacterial spore germination
Lei Rao, Tianyu Zhang, Ziqi Gong, Ke Liu, Yonggang Wang, Bing Zhou, Yongqiang Gao, Peter Setlow, Xiaojun Liao
This study shows that pressure-induced membrane tension opens the GerA ion channel in Bacillus subtilis spores, triggering germination through a stretch-to-open mechanism.
mBio · Oct 30, 2026Peer-reviewedMicrobiology