Peter Setlow

This study shows that pressure-induced membrane tension opens the GerA ion channel in Bacillus subtilis spores, triggering germination through a stretch-to-open mechanism.

The paper identifies water-contact residues in GerAB that are critical for germinosome stability in Bacillus subtilis spores, based on MD simulations and functional assays.

The paper develops a mathematical model to explain memory in Bacillus subtilis spore germination, showing that GR states and SpoVA channel dynamics are crucial for memory.

The paper identifies three key residues in GerAB that affect water passage and germinosome stability through mutagenesis and molecular dynamics simulations.

This paper introduces a new sample preparation method, SPEED, which improves proteomic analysis of Bacillus subtilis spores by identifying more proteins and enabling differentiation between spore and vegetative cell proteins.