Effective structure-aware protein alignment via residue-level contrastive learning
Ronghui You, Ziye Wang, Kunpeng Liu, Wei Zheng, Qiqige Wuyun, Yuhao Yi, Shanfeng Zhu
CLAlign improves protein alignment by using contrastive learning to generate structure-aware embeddings, outperforming both unsupervised and sequence-based methods.
bioRxiv · Mar 9, 2024 · PreprintBioinformatics