Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development
Jasmin Morandell, Lena A. Schwarz, Bernadette Basilico, Saren Tasciyan, Georgi A. Dimchev, Armel Nicolas, Christoph Sommer, Caroline Kreuzinger, Christoph P. Dotter, Lisa S. Knaus, Zoe Dobler, Emanuele Cacci, Florian K. M. Schur, Johann Georg Danzl, Gaia Novarino
This study shows that Cul3 mutations in mice cause ASD-like behaviors and neuronal migration defects during brain development, but not in adults.
Nature Communications · May 24, 2021Peer-reviewedNeuroscience