Author

Lena A. Schwarz

Institute of Science and Technology Austria

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Bernadette BasilicoiD· 2 shared Gaia NovarinoiD· 2 shared Lisa S. Knaus· 2 shared Alasdair L. A. VanceiD· 1 shared Alysa E. DoyleiD· 1 shared Ana I. Cubillo· 1 shared Anastasia ChristakouiD· 1 shared Anders Martin DaleiD· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersNeuroscience

Bernadette BasilicoORCID

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Author profile →

3 papers

Recent·Most cited

Large neutral amino acid levels tune perinatal neuronal excitability and survival

Lisa S. Knaus, Bernadette Basilico, Daniel Malzl, Maria Gerykova Bujalkova, Mateja Smogavec, Lena A. Schwarz, Sarah Gorkiewicz, Nicole Amberg, Florian M. Pauler, Christian Knittl‐Frank, Marianna Tassinari, Nuno Maulide, Thomas Rülicke, Jörg Menche, Simon Hippenmeyer, Gaia Novarino

The paper investigates how changes in large neutral amino acid metabolism during development affect neuronal excitability and survival, finding that Slc7a5 deletion disrupts lipid metabolism and leads to long-term circuit dysfunction.

Cell · Mar 29, 2023Peer-reviewedNeuroscience

Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development

Jasmin Morandell, Lena A. Schwarz, Bernadette Basilico, Saren Tasciyan, Georgi A. Dimchev, Armel Nicolas, Christoph Sommer, Caroline Kreuzinger, Christoph P. Dotter, Lisa S. Knaus, Zoe Dobler, Emanuele Cacci, Florian K. M. Schur, Johann Georg Danzl, Gaia Novarino

This study shows that Cul3 mutations in mice cause ASD-like behaviors and neuronal migration defects during brain development, but not in adults.

Nature Communications · May 24, 2021Peer-reviewedNeuroscience

Evidence for Similar Structural Brain Anomalies in Youth and Adult Attention-Deficit/Hyperactivity Disorder: A Machine Learning Analysis

Yanli Zhang‐James, Emily C. Helminen, Jinru Liu, The ENIGMA-ADHD Working Group, Geraldo F. Busatto, Anna Calvo, Mara Cercignani, Tiffany M. Chaim‐Avancini, Matt C. Gabel, Neil Andrew Harrison, Luisa Lázaro, Sara Lera‐Miguel, Mario Rodrigues Louzã, Rosa Nicolau, Pedro G. P. Rosa, , Susanne Walitza

This study uses machine learning to show that structural brain anomalies in ADHD are similar in children and adults, supporting continuity of the disorder's pathophysiology.

Translational Psychiatry · Feb 1, 2021Peer-reviewedBioinformatics