Bernadette Basilico

The paper investigates how missense mutations in the SynGAP C2 domain affect membrane diffusion dynamics through molecular simulations and structural analysis.

This study shows that complement signaling via C3r is critical for perinatal neuronal elimination but not synaptic pruning in the developing brain.

The paper investigates how changes in large neutral amino acid metabolism during development affect neuronal excitability and survival, finding that Slc7a5 deletion disrupts lipid metabolism and leads to long-term circuit dysfunction.

This study shows that microglia regulate glutamatergic synapses in adult mouse hippocampus, with their removal causing reversible synaptic and behavioral changes.

This study shows that Cul3 mutations in mice cause ASD-like behaviors and neuronal migration defects during brain development, but not in adults.