Lost and found: beer belly is a novel, ancient regulator of animal development
Zoe X. Schultz, Grace Blakeley, Madeleine E Aase-Remedios, Dorothea V. Grillmayer, Daniel J. Leite, Tom Frankish, Gemma Sutton, Grigory Genikhovich, Steffen Scholpp, Matthias Pechmann, José María Martín-Durán, Natascha Turetzek, Ralf Janßen, Alistair P. McGregor
The paper identifies a novel gene, beer belly, as a regulator of segmentation in spiders using single-cell RNA sequencing and shows its evolutionary loss in mammals and holometabolous insects.
bioRxiv · Oct 27, 2026 · PreprintDevelopmental Biology