Alistair P. McGregor

The paper identifies a novel gene, beer belly, as a regulator of segmentation in spiders using single-cell RNA sequencing and shows its evolutionary loss in mammals and holometabolous insects.

This paper shows how the spider venom gland evolved by integrating three distinct developmental programs: appendage patterning, secretory epithelium maintenance, and myogenic metabolism.

The paper investigates ZGA timing across 61 animal species and finds that genome size to cytoplasm volume ratio predicts ZGA onset.

The paper examines head patterning in a spider, identifying neurosecretory centres and pioneer neurons, providing new insights into arthropod development and evolution.

The paper compares gene expression and chromatin accessibility of ohnologues and single-copy genes in two arachnids, one with a history of whole genome duplication, to assess subfunctionalization.

The paper characterizes visual system development in eight spider species to understand how diverse eye configurations arise and evolve.

The paper investigates the role of C15, Lim1, and Al in the development of male and female Drosophila terminalia, finding sex-specific expression and regulatory interactions.

This study investigates venom gland development in the common house spider using bulk RNA-seq and in situ hybridization, identifying key markers and developmental stages.

The paper constructs a single-cell RNA sequencing atlas of spider embryos, revealing cell clusters, gene expression patterns, and developmental insights into arthropod embryogenesis.

This study investigates how Ultrabithorax (Ubx) regulates fine-scale leg morphology in Drosophila by identifying enhancers, co-factors, and transcription factors involved in trichome patterning.

The paper examines retention of ohnologs in developmental gene families across arachnopulmonate species, finding extensive retention and evolutionary patterns in Hox, Wnt, and frizzled genes.

This study examines Sox gene repertoires and regulation of segmentation in arachnids, finding Sox21b-1 plays distinct roles in prosomal and opisthosomal segmentation.

The paper analyzes gene and protein domain content changes across 76 arthropod genomes to understand evolutionary patterns and their association with phenotypic adaptations.

This study investigates the role of a SoxB gene in spider segmentation, finding it regulates posterior segment addition and interacts with Wnt8 and Delta-Notch signaling.

This study examines Sox gene duplication and divergence in spiders, finding retained duplicates, neofunctionalization, and conserved roles in CNS development and segmentation.

The paper analyzes the house spider genome to identify an ancient whole-genome duplication shared by spiders and scorpions, distinct from horseshoe crab duplications.