Mhaned Oubounyt

NetMap jointly infers cell-level gene regulatory networks and clusters cells based on shared regulatory programs, outperforming existing methods on synthetic data and reliably detecting regulons on real data.

The paper develops an integrated single-cell and spatial transcriptomics atlas of healthy human skin, focusing on the pilosebaceous unit, and identifies previously under-characterized cell types and signaling hubs.

The paper introduces Scellnetor, a tool to identify systems biology patterns in pseudo-temporal trajectories from scRNA-seq data, applied to hematopoiesis and CD8 T-cell development.