Benjamin Al

The paper investigates the molecular mechanisms of comedogenesis in human acne using single-cell transcriptomics, identifying a microcomedone-like cell population and supporting the comedone switch hypothesis.

This paper develops a co-culture system of human keratinocytes and iPSC-derived sensory neurons to model AD itch, showing TRPA1 and JAK1/2 inhibition reduce pruritogen responses.

The paper develops an integrated single-cell and spatial transcriptomics atlas of healthy human skin, focusing on the pilosebaceous unit, and identifies previously under-characterized cell types and signaling hubs.