Pattern formation along signaling gradients driven by active droplet behaviour of cell groups
Hugh Z. Ford, Giulia L. Celora, Elizabeth R. Westbrook, Mohit P. Dalwadi, Benjamin J. Walker, Hella Baumann, Cornelis Jan Weijer, Philip Pearce, Jonathan Robert Chubb
The paper shows that Dictyostelium cells form swarms that behave like active droplets, leading to clump deposition and differentiation through a 'musical chairs' mechanism.
Proceedings of the National Academy of Sciences · May 20, 2025Peer-reviewedBiophysics