BiochemistrybioRxivPreprint
Structural basis for anomalous cellular trafficking behavior of glaucoma-associated A427T mutant myocilin
Kamisha R. Hill, Hailee F. Scelsi, Hannah A. Youngblood…·Raquel L. Lieberman
This study investigates the structural and cellular behavior of the A427T myocilin mutant, showing structural similarity to wild-type but inefficient degradation, which contributes to glaucoma pathogenesis.
DOI 10.1101/2025.02.26.640437