Author

Hannah A. Youngblood

Georgia Institute of TechnologyORCID 0000-0002-8326-7282Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

Raquel L. LiebermaniD· 2 shared Donna M. Pesciotta PetersiD· 1 shared Ethan F. Harris· 1 shared Hailee F. ScelsiiD· 1 shared Jennifer A. FaralliiD· 1 shared John D. HullemaniD· 1 shared Kamisha R. HilliD· 1 shared Kaylee P. LankfordiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

Raquel L. LiebermanORCID

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2 papers

Recent·Most cited

Monitoring mutant myocilin secretion and localization in trabecular meshwork cell cultures using a protein complementation-based luminescence assay

Hannah A. Youngblood, Ethan F. Harris, Kaylee P. Lankford, Victoria Garfinkel, John D. Hulleman, Raquel L. Lieberman

This paper introduces a luminescence assay to detect myocilin secretion defects in trabecular meshwork cells and confirms secretion issues for several mutant variants.

Experimental Eye Research · Mar 3, 2025Peer-reviewedBiochemistry

Structural basis for anomalous cellular trafficking behavior of glaucoma-associated A427T mutant myocilin

Kamisha R. Hill, Hailee F. Scelsi, Hannah A. Youngblood, Jennifer A. Faralli, Tatsuo Itakura, M. Elizabeth Fini, Donna M. Pesciotta Peters, Raquel L. Lieberman

This study investigates the structural and cellular behavior of the A427T myocilin mutant, showing structural similarity to wild-type but inefficient degradation, which contributes to glaucoma pathogenesis.

bioRxiv · Feb 26, 2025 · PreprintBiochemistry