Author

Deborah Ness

King's College LondonORCID 0000-0001-5047-1132Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:protein structure· 2 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Alfredo IacoangeliiD· 2 shared Ammar Al‐ChalabiiD· 2 shared Munishikha KaliaiD· 2 shared Richard DobsoniD· 2 shared A Nazli Basak· 1 shared Adriano Chio· 1 shared Ahmad Al KhleifatiD· 1 shared Albert Ludolph· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Alfredo IacoangeliORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintMar 22, 2023

Mutafy: A webserver to identify high quality mutant protein structures in the Protein Data Bank

Deborah Ness, Jiajing Hu, Munishikha Kalia…·Alfredo Iacoangeli

Mutafy identifies high-quality mutant protein structures from the PDB for given human genes, annotates them with biomedical data, and provides interactive visualization.

DOI 10.1101/2023.03.22.533870

humanprotein structure

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NeuroscienceComputational and Structural Biotechnology JournalPeer-reviewedJan 1, 2023

Molecular dynamics analysis of Superoxide Dismutase 1 mutations suggests decoupling between mechanisms underlying ALS onset and progression

Munishikha Kalia, Mattia Miotto, Deborah Ness…·Alfredo Iacoangeli

This study uses molecular dynamics and clinical data to show structural and dynamic differences between WTL and MBR SOD1 variants, linking these to distinct ALS clinical outcomes.

19 citations

humanprotein structure

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