Shuai Yuan

This study evaluates polygenic risk scores for hernia susceptibility and finds they are associated with incisional hernia but do not improve clinical risk prediction beyond traditional factors.

This study identifies 243 genome-wide significant loci for hernia subtypes, reveals shared and distinct genetic factors, and identifies potential therapeutic targets.

This study uses Mendelian randomization to show IL-1Ra increases CHD risk, which is reversed by apolipoprotein B adjustment and lifestyle interventions.