Author

Olaf Merkel

Medical University of ViennaORCID 0000-0001-5089-344XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Lukas KenneriD· 2 shared Michaela SchledereriD· 2 shared Adam Varady· 1 shared Alejandro Medaglia Mata· 1 shared Aleksandra Fesiuk· 1 shared Boglárka SzabóiD· 1 shared Boris TichýiD· 1 shared Brigitte HantuschiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCancer Biology

Lukas KennerORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMar 30, 2026

Single-Cell Profiling Reveals Developmental Trajectories and identifies SYK and TIM3 as Targets in some T Cell Lymphomas

Ruoyan Li, Jamie D. Matthews, Emily R. James…·Suzanne Dawn Turner

This study uses single-cell transcriptomics to analyze T cell lymphomas, identifies developmental origins, and discovers SYK and TIM3 as potential therapeutic targets.

DOI 10.64898/2026.03.27.714741

humanscRNA-seq

𝕏 PostBluesky

Cancer BiologyMolecular CancerPeer-reviewedOct 14, 2025

Thyroid Hormone Receptor Beta Signaling is a Targetable Driver of Prostate Cancer Growth

Aleksandra Fesiuk, Daniel Pölöske, Elvin D. de Araujo…·Lukas Kenner

This study identifies TRβ as a driver of prostate cancer growth and shows that NH-3 inhibits PCa cell proliferation and tumor growth, particularly in castration-resistant models.

DOI 10.1186/s12943-025-02451-2

humanbulk RNA-seq

𝕏 PostBluesky