Lei Gu

M6AFormer identifies unannotated m6A sites in the human transcriptome, showing their association with genetic variants and disease mechanisms, and validates one site's functional impact on cancer cell migration.

The paper introduces an integrated workflow for high-throughput single-cell proteomics, achieving high throughput and protein identification using SPRINT and dual-spray LC-MS.

This study identifies the genetic architecture of the S-locus supergene in tetraploid Schizomussaenda henryi, revealing hemizygous genes, gene duplication, and the role of auxin signaling in style length regulation.

The paper develops ultrasensitive proteome technologies for single-cell and low-input mouse embryos, enabling high-depth protein identification with minimal starting material.

This paper introduces LCM-MTA, a method for spatially resolved proteomics of trace FFPE tissues, improving sensitivity, recovery, and integrality.

The paper introduces a single-cell proteomic workflow that achieves high sensitivity and throughput for protein quantification in human cell lines.