Andrew J. Hirning

This paper presents a method to control microbial consortium proportions using auxotrophic cross-feeding in continuous culture, demonstrating precise regulation through exogenous nutrient addition and mathematical modeling.

This paper demonstrates how to tune gene circuit dynamics in a synthetic microbial consortium by adjusting strain fractions, creating a pulse generator with controllable amplitude.

The paper demonstrates how microdroplet confinement can indirectly enrich a rare producer strain in a synthetic microbial community through spatial structure and metabolite diffusion.

This study investigates how trap size in microfluidic devices affects the spatiotemporal dynamics of synthetic microbial consortia, revealing a trade-off between signaling effectiveness and strain proportion stability.