GenomicsArchives of ToxicologyPeer-reviewed
Detection of genome-wide low-frequency mutations with Paired-End and Complementary Consensus Sequencing (PECC-Seq) revealed end-repair derived artifacts as residual errors
Xinyue You, Suresh Thiruppathi, Weiying Liu…·Takayoshi Suzuki
The paper introduces PECC-Seq, a PCR-free method for detecting low-frequency mutations, and identifies end-repair artifacts as a major source of sequencing errors.
30 citations