Author

Yang Luan

Shanghai Jiao Tong UniversityORCID 0000-0002-2211-7803Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:benchmarking· 1 Organism:C. elegans· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Organism:mouse· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Yiyi CaoiD· 2 shared Cao LiiD· 1 shared Chenye SheniD· 1 shared Chie FurihataiD· 1 shared Chunbo LiuiD· 1 shared Fang HuangiD· 1 shared Fangzheng CheniD· 1 shared Guangchun Fan· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersBioengineering

Yiyi CaoORCID

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3 papers

Recent·Most cited

Inhibition of CGRP receptor ameliorates AD pathology by reprogramming lipid metabolism through HDAC11/LXRβ/ABCA1 signaling

Guangchun Fan, Fangzheng Chen, Min Liang, Ping Yang, Hongtian Dong, Jing Su, Mengqi Wang, Ziyuan Wang, Penggang Ning, Chenye Shen, Xiwen Tang, Xin Yan, Haoxiang Lin, Jiayin Zhao, Yunhe Zhang, , Fang Huang

This study shows that inhibiting the CGRP receptor reduces AD pathology by reprogramming lipid metabolism via the HDAC11/LXRβ/ABCA1 signaling pathway in both human and mouse models.

bioRxiv · Oct 17, 2025 · PreprintNeuroscience

An automated microfluidic platform for toxicity testing based on Caenorhabditis elegans

Jiaying Wu, Jing Xi, Zhouhai Zhu, Wei Zhao, Qiyuan Peng, Chunbo Liu, Ziqian Wan, Yiyi Cao, Xiang Chen, Yang Luan

This paper introduces an automated microfluidic platform using C. elegans to assess chemical toxicity, showing it can evaluate general and developmental impacts of chemicals.

bioRxiv · Aug 27, 2024 · PreprintBioengineering

Detection of genome-wide low-frequency mutations with Paired-End and Complementary Consensus Sequencing (PECC-Seq) revealed end-repair derived artifacts as residual errors

Xinyue You, Suresh Thiruppathi, Weiying Liu, Yiyi Cao, Mikihiko Naito, Chie Furihata, Masamitsu Honma, Yang Luan, Takayoshi Suzuki

The paper introduces PECC-Seq, a PCR-free method for detecting low-frequency mutations, and identifies end-repair artifacts as a major source of sequencing errors.

Archives of Toxicology · Jul 31, 2020Peer-reviewedGenomics