Agent-based modeling of the prostate tumor microenvironment uncovers spatial tumor growth constraints and immunomodulatory properties
Maisa N.G. van Genderen, Jeroen Kneppers, Anniek Zaalberg, Elise M. Bekers, Andries Marinus Bergman, Wilbert T. Zwart, Federica Eduati
This study uses an agent-based model to simulate prostate cancer growth and ADT effects, revealing CRPC development and immunomodulatory interactions in the tumor microenvironment.
npj Systems Biology and Applications · Feb 21, 2024Peer-reviewedSystems Biology