Sanjeeva Srivastava

Extending structural surfaceomics to identify aberrant conformations of tumor surface proteins as potential immunotherapy targets

This paper expands structural surfaceomics to identify cancer-specific protein conformations across multiple tumor models, revealing potential immunotherapy targets through crosslinking mass spectrometry and structural modeling.

DrugProtAI: A guide to the future research of investigational target proteins

The paper introduces DrugProtAI, a tool that predicts druggability of proteins and evaluates 20,273 human proteins, achieving a median AUC of 0.86 in target predictions.

BrainProt(™) 3.0: Understanding Human Brain Diseases using comprehensively curated & Integrated OMICS datasets

BrainProt 3.0 integrates multi-omics data to provide a resource for understanding human brain diseases and identifying therapeutic strategies.

Proteomic analysis of liver tissue reveals Aeromonas hydrophila infection mediated modulation of host metabolic pathways in Labeo rohita

The paper uses proteomic analysis to identify changes in the host liver proteome during Aeromonas hydrophila infection in Labeo rohita, revealing dysregulated metabolic and immune pathways.