MicrobiologybioRxivPreprint
HIV lymphoid tissue fibrosis occurs in the earliest stages of acute HIV infection and is associated with macrophage-derived TGF-β
Jodi L. Anderson, Carlo Sacdalan, Somchai Sriplienchan…·Timothy W. Schacker
The paper shows HIV causes collagen deposition in lymphoid tissue early in infection, linked to TGF-β+ macrophages and HIV RNA-producing cells, suggesting early ART may not prevent fibrosis.
DOI 10.64898/2026.02.02.703316