MicrobiologybioRxivPreprint
Epistasis facilitates the long-term antigenic evolution of the influenza B virus hemagglutinin
Lara S. U. Schwab, Ruopeng Xie, Ellie Reilly…·Marios Koutsakos
The paper analyzes the antigenic evolution of influenza B virus hemagglutinin over 8 decades, identifying epistatic networks that balance antigenic novelty with viral fitness.
DOI 10.64898/2026.07.22.739994