NeurosciencebioRxivPreprint
Tau conformers in FTLD-MAPT undergo liquid-liquid phase separation and perturb the nuclear envelope
Sang‐Gyun Kang, Zhuang Zhuang Han, Nathalie Daude…·David A. Westaway
The paper shows that tau conformers in FTLD-MAPT undergo liquid-liquid phase separation and disrupt nuclear envelope function, leading to cell death and fibrillar structures.