Tatiana Belova

SiSaNA provides a command line interface for single-sample regulatory network analysis without requiring programming experience.

The paper benchmarks clustering strategies for patient-specific gene regulatory networks across 9,778 cancer samples, finding that standard deviation-based feature selection with k-means performs best.

The paper analyzes gene regulatory networks across 9,000 tumors to identify recurrent PD-1 pathway dysregulation linked to patient outcomes.

This study integrates multi-omics data with gene regulatory networks to improve survival predictions in ten cancer types, showing improved associations with patient survival when GRNs are included.

The paper analyzes gene regulatory networks in Physcomitrium patens to show DEK1 calpain gates cell fate transitions through deregulated regulons and sequential developmental transitions.

The paper develops a computational framework to identify regulatory heterogeneity in leiomyosarcoma by analyzing gene regulatory networks and validates findings in independent datasets.

The paper identifies PD1 signaling regulation as a prognostic marker in glioblastoma using gene regulatory network analysis across two cohorts.