Author

Amy R. Eggers

Innovative Genomics InstituteORCID 0000-0001-5249-4872Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Brittney W. ThorntoniD· 1 shared Bryant XuiD· 1 shared Erin E. DohertyiD· 1 shared Jennifer A. DoudnaiD· 1 shared Kai CheniD· 1 shared Katarzyna M. SoczekiD· 1 shared Marena I. TrinidadiD· 1 shared Owen T. TuckiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperMolecular Biology

Brittney W. ThorntonORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Rapid DNA unwinding accelerates genome editing by engineered CRISPR-Cas9

Amy R. Eggers, Kai Chen, Katarzyna M. Soczek, Owen T. Tuck, Erin E. Doherty, Bryant Xu, Marena I. Trinidad, Brittney W. Thornton, Peter H. Yoon, Jennifer A. Doudna

The paper shows that engineered GeoCas9 variants enhance genome editing by accelerating DNA unwinding, revealing a new role for the WED domain in this process.

Cell · May 22, 2024Peer-reviewedMolecular Biology