Amit Blumberg

The paper introduces a method to estimate RNA half-lives using PRO-seq and RNA-seq data, finding correlations between RNA stability and splicing, miRNA binding, DNA methylation, and histone modifications.

The paper identifies a conserved DNase-I footprinting pattern across human mtDNA, suggesting a regulated protein-DNA organization involved in mtDNA transcription.

The paper examines co-expression of mitochondrial and nuclear OXPHOS genes across human tissues, finding positive co-expression in most tissues but negative correlation in ancient brain regions.

The paper uses deep sequencing to analyze mtDNA transcription in human and metazoan organisms, revealing conserved pausing sites and divergence across species.